Saturday, February 28, 2015

Cut Sugar Not Cholesterol

About 20 years ago good studies began to appear in leading journals noting that the real problem with arterial disease is not cholesterol, but sugar. This was at that time and probably still is now, a bit shocking to those who have unquestioningly accepted Big Pharma’s demonizing of cholesterol, [1] a natural molecule needed to patch up leaky arteries, make hormones, and synthesize cell membranes, particularly neurons.

To make a long story short, excessive and processed sugars cause insulin resistance throughout the body. In the liver it causes FATTY LIVER, which leads to poor handling of cholesterol. Because of this and inflammation/oxidation related to insulin resistance, both cholesterol and the lining of the arteries become sticky. This leads to poor patching of arterial leakiness, which results in plaque formation.

If the above were to be addressed with a good diet low in refined sugars, cholesterol would not be a problem in most people. This is why the American Heart Association has recommended TLC first, or Therapeutic Lifestyle Changes before using Statin drugs to lower cholesterol. In other words, it is possible to have high cholesterol and not develop arterial disease. The American Medical Association just published a report noting that if a CT scan shows your coronary arteries clear of calcium deposits, you do not need a Statin drug even though your cholesterol may be elevated. [2] Incidentally, Statin drugs are no more beneficial than an apple a day… [3]

Twenty years ago I had a cardiologist angrily criticize me for saying that sugars are more toxic than cholesterol. I wonder if he will take the time to read the 2015 Dietary Guidelines from the Advisory Committee’s to the Secretary of Health and Human Services and Secretary of Agriculture published February 2015. They are summarized below:

WASHINGTON, DC — “ An expert panel has released its new recommendations to the US government for healthy eating in a 570-page report that provides some new advice and supports a pattern that promotes health and prevents disease.

Published this week, the recommendations include advice staples such as focusing on the consumption of fruit, vegetables, whole grains, low- or nonfat dairy, seafood, legumes, and nuts and limiting the consumption of red and processed meat, added sugars, and refined grains. But the recommendations also include some twists, such as giving a green light to a moderate amount of caffeine consumption and no longer trying to control the amount of dietary cholesterol Americans eat.

"Strong evidence shows that it is not necessary to eliminate food groups or conform to a single dietary pattern to achieve healthy dietary patterns," according to Dr Barbara Millen (Millennium Prevention, Westwood, MA) and Dr Alice Lichtenstein (Tufts University, Boston, MA), the chair and cochair of the 2015 Dietary Guidelines Advisory Committee (DGAC), and their coauthors. "Rather, individuals can combine foods in a variety of flexible ways to achieve healthy dietary patterns, and these strategies should be tailored to meet the individual's health needs, dietary preferences, and cultural traditions."

The recommendations from the committee, 18 months in the making, cite "new scientific evidence" to inform the revisions to the 2010 Dietary Guidelines for Americans . The review of the evidence and their recommendations were presented to the US Departments of Health and Human Services and Agriculture. The departments, which are responsible for writing the US dietary guidelines, will consider the recommendations when they draft their final report later this year.

In the US, approximately 155 million individuals are overweight or obese and 117 million individuals have chronic, preventable diseases.

Taking the Long View

In terms of one of the most important changes, the advisory committee, which is made up of physicians and nutritionists, takes the long view on the nation's food supply and focuses on the sustainability of food choices, something it has not done in the past. As part of the evidence review, the committee said it examined the near- and long-term sustainability of healthy dietary patterns and components of the modern diet, such as caffeine.

There is moderate to strong evidence showing that healthy dietary patterns rich in plant-based foods, such as vegetables, fruits, whole grains, legumes, nuts, and seeds, as well as lower-calorie animal-based foods, are associated with more favorable environmental outcomes, such as lower greenhouse-gas emissions and more favorable land, water, and energy use, according to the DGAC.

"Healthy, sustainable dietary patterns also may provide new themes for consumer education and communication on lifestyle practices that can promote food security now and for future generations and create a 'culture of health' at individual and population levels," they add.

Some Surprises in the Report

Aside from accounting for the environmental aspects of food, the committee includes a few more surprises in the report. For example, the recommendations diverge slightly from past guidelines in that they no longer put a limit on the amount of dietary cholesterol individuals should eat.

In the 2010 dietary guidelines, the daily cholesterol target was set at less than 300 mg. Now, says the committee, dietary cholesterol is "not considered a nutrient of concern for overconsumption" and current evidence suggests there is "no appreciable relationship" between heart disease and dietary cholesterol.

The recommendations also provide good news for coffee lovers in that caffeine is no longer considered an enemy of the people. In fact, the advisory committee says consuming three to five cups of coffee per day can be part of a healthy diet and that data to date suggest that coffee reduces the risk of type 2 diabetes and cardiovascular disease. This amounts to approximately 400 mg of caffeine per day. The consumption of added sugar, fatty milk, or rich creams with the coffee, though, is not advised.

Regarding sodium, the DGAC points out that Americans still consume way too much, with the average individual consuming nearly 3500 mg per day. As part of the dietary recommendations, the goal is for individuals to cut at least 1000 mg of sodium from their daily diet to get daily intake down to 2300 mg per day, a recommendation in line with the Institute of Medicine . The advisory committee no longer recommends a daily target of 1500 mg for any individuals, even those with hypertension, diabetes, or chronic kidney disease.

The committee also recommends consuming no more than 10% of daily calories from saturated fat. Regarding added sugars, the same rule applies, with the recommendation that no more than 10% of calories come from added sugar. This amounts to just 12 teaspoons of sugar per day. Currently, the average American takes in anywhere from 22 to 30 teaspoons daily, often in the form of juices and sugar-laden drinks.

To combat how much sugar is consumed in the US, especially by kids in the form of pop and energy drinks, the guideline authors say that water is the preferred beverage choice. "Strategies are needed to encourage the US population, especially children and adolescents, to drink water when they are thirsty," they write 2015 Dietary Guidelines Advisory Committee .”

Advisory report to the Secretary of Health and Human Services and Secretary of Agriculture. Published February 2015

[1] “What if Fat Doesn’t Make you Fat,” York Times Magazine July 7th 2002

[2] AMA Scientific Session Chicago 2015

[3] “A statin a day keeps the doctor away: comparative proverb assessment modeling study,” BMJ 2013; DOI: 10.1136/bmj.f7267. Available at:

Wednesday, February 25, 2015

Curcumin-Turmeric: A Test of View on Science

The current issue of the National Geographic magazine (March 2015) has an article by Mr. Achenbach, a Washington Post staff writer. He opines that any questioning of “established scientific facts” demonstrates ignorance, denial, and even conspiratorial beliefs. He cites opposition to vaccination, fluoridation and GMOs as examples, issues we have covered in this newsletter. It is not the intention of this blog to prove or disprove those controversial issues, but, to point out some scientific principles Mr. Achenbach did not cover. It is up to you to examine the scientific literature on both sides.

One, science is a never ending quest for truth. It should include a high dose of humility to allow for the fact that each new discovery simply opens another veil yet to be the subject of further search. Closing our minds to further developments in science has been catastrophic. History is littered with such examples.

Two, a true scientist is indeed by definition a skeptic. This does not mean one is to reject opposing points of view, but that we need to be open to consider the evidence regardless of preconceived notions. Does Galileo ring a bell?

Three, we must question the sources from which we get information. Often, money is behind categorical statements that attack, or ridicule the opposition. “The Manufacturing of Consent” ought to ring another bell: google that. For instance, you should study my background. I am happy to report I do not get involved in marketing or selling of any products. As for Mr. Achenbach, he is edited by his newspaper, which is heavily influenced by its advertisers (Monsanto, Big Pharma, etc.)

What does Curcumin have to do with this issue?

Ask about it when you are attempting to gauge someone’s attitudes about non pharmaceutical treatments. If they categorically tell you there is no scientific evidence for the use of curcumin you will know where they are coming from.

Curcumin, as often reported herein is soon to be marketed as an adjuvant, or synergistic agent for cancer chemotherapy. It is also an excellent antioxidant, anti-inflammatory herb, much like aspirin, but no side effects. As such it compares well with Ibuprofen. It thins the blood a bit, so, it is helpful in diseases that promote clotting. Curcumin also lowers insulin resistance and blood pressure. All these salutary actions must have a common denominator. Indeed, it is a good antioxidant, anti inflammatory herb/spice that improves our metabolism. [1]

[1] “Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis,” J. Clinical Nutrition Published Online: January 07, 2015