Sunday, December 29, 2013

Depression treatment and “Psychobiotics: a novel class of psychotropic.”1

The Brain-Gut connection is highlighted in medical journals fairly often these days. Unfortunately, it is not getting much discussion in clinics where depression is quickly diagnosed and treated with medications that often have side effects and questionable results. 
This is not a call to give up on a pharmaceutical approach to depression treatment, but to encourage patients and health care providers to consider dietary interventions and cognitive therapy (counselling, mending relationships, forgiving, etc.) before reflexively prescribing pharmaceuticals. Some patients must have them; but, depression is often over-diagnosed and definitely over-treated with pharmaceuticals. It is estimated that only 38% of cases merit antidepressants. 2 They should be reserved for the most serious cases of depression. 3
The article (title) above shows that patients with depression and other psychiatric diagnoses are often found to be lacking in certain healthy bacteria in the gut. This is why the term “psychobiotics” has been coined. Poor diets, too much sugar, not enough fiber, too many acid blocking pills and antibiotics, and even certain antidepressants (Mirtazapine and Fluoxetine) 4 may compromise our gut flora. According to this article, the benign gut flora B. infantis may be used for depression. L. helveticus and L. rhamnosus may be used for anxiety.  They work on GABA receptors which improves dopamine function in the brain: feed your gut flora real food.
Happy New Year!

1 J. Biological Psychiatry 2013;74:708
2 J. Family Practice News May 15th 2013, page 1
British J. of Medicine 2012;344:e4211
4 Epub May 7th J. BMC Medicine


Post a Comment

Subscribe to Post Comments [Atom]

<< Home